Despite being an effective treatment for hair loss, oral Finasteride has become a subject of concern. Topical Finasteride for Hair Loss | Happy Head side effects are way worst. pros I've heard so far: way more effective. It's to be used twice a day preferable in the morning and evening everyday. Dr. Nichole Rogers-Review of finasteride-Oral and Topical ... Minoxidil is a topical treatment applied to your scalp twice a day. Low-Dose Oral Minoxidil Deemed Safe for Hair Growth ... It was originally marketed for BPH at 5mg daily, one of the side effects noticed with this medication was the increasing . Five patients took a break of 8-12 months in between oral and topical therapy. Ultimately, the team concluded that both groups — oral and topical — saw similar results. Oral Minoxidil for Hair Loss: Is It a Better Treatment ... Their formulations are personalized, meaning that exact . A randomized, double-blind controlled clinical study to ... National Library of Medicine - National Institutes of Health Does Topical Finasteride Work? Everything You Need To Know Results showed that 80% to 84.4% of these patients maintained good hair density while on the topical combination of minoxidil 5% . Oral finasteride was found to be more effective than minoxidil in patients with moderately severe AGA [6]. Minoxidil or Finasteride for Hair Loss? What Works Best So, if you don't have any oral Finasteride side effects then you can take it and include 5% topical Minoxidil. It's more advantageous to investigate using the 2% of 5% version of topical minoxidil to fight hair loss. Effectiveness and Safety of Low-Dose Oral Minoxidil in ... Topical vs. oral finasteride for hair loss. What To Expect When Switching From Topical To Oral Minoxidil Between the two, Minoxidil has been around longer. Finasteride and minoxidil may help slow down male- and female-pattern hair loss, and in some cases may even cause lost hair to . Finasteride is a pill, which you take orally once a day. Minoxidil oral, on the . Topical finasteride may not be for everyone. The men were randomized to receive dutasteride 0.02, 0.1, or 0.5 mg/day, finasteride 1 mg/day, or placebo. View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions. The benefit of oral minoxidil over topical minoxidil is several fold. It was developed all the way back in the '50s. From what I've read it speeds up aging but a lot of info I get from hair loss sites that tend to exaggerate the effects (ex: saying they you will age 10 years in 1 year). All in all, yes. Its main purpose was as an antihypertensive agent. Side effects of oral minoxidil therapy are dose related and include low blood pressure, increased heart rate and fluid retention (see page 3). The potential side effects of topical Dutasteride may be found to be similar to the closely related medication, Finasteride, which has been found to have mainly minor reactions . Unlike Propecia, Rogaine works by stimulating the hair follicle itself to help encourage hair regrowth. Since 1997, topical minoxidil has been available over the counter as a generic and under a wide variety of brand names. I've heard people microdosing it at 2.5mg. Background and aim: Androgenetic alopecia (AGA) is undoubtedly the most common form of hair loss in males. 4. How Rogaine (Minoxidil) Works. The study found that approximately 84 percent of the participants who were . INTRODUCTION. Each group continued treatment for 12 months. Topical finasteride is a clinically proven, modern, effective method of combating hair loss with possible lower systemic adverse effects, according to clinical studies. 83% of the finasteride-treated group and 81% of the . Finasteride at 1 mg/day and 5% topical minoxidil are effective in male androgenetic alopecia (MAGA). Oral minoxidil is available only by prescription. Welcome to the National Library of Medicine, the world's largest biomedical library and the center of biomedical informatics and computational biology at NIH. The difference was not statistically significant but the oral minoxidil group also had less hair shedding. And if you want to increase your odds to 94% from the percentages above, the same clinical study (and many others!) Oral minoxidil was found to be an effective and well-tolerated treatment alternative for healthy patients having difficulty with topical formulations. In the study, twelve participants experienced adverse reactions, which represents 29.3% of the entire clinical trial. Topical minoxidil is received very well by the general population, with a tiny percentage of men and women experiencing adverse reactions. It is much more effective than minoxidil alone, and it is more cost effective than taking oral finasteride.". Updated to include the latest in surgical hair restoration, FUE, medical treatments, hair cloning and laser therapy. In addition, oral minoxidil does not need to be converted by the skin into minoxidil sulphate. One of the main causes of hair loss is Dihydrotestosterone (DHT). While both prevent hair loss and stimulate hair growth, one does it at the topical level while the other is a hormonal medicine that prevents hair loss at its source. In a 2002 study researching strength effectiveness, researchers found after 48 weeks, the group using 5% minoxidil had 45% more hair growth vs. those using 2% minoxidil. A common treatment advised by dermatologists all around the world, topical minoxidil (TM) is an FDA approved medication for patterned hair loss. Oral minoxidil comes in a form of a tablet. 83% of the finasteride-treated group and 81% of the . First, the patient uses a pill and does not need to use something that potentially affects how the hair looks day to day. At the 12 month mark, the participants were asked if they would like to continue treatment for another year. Prices On average, the cost for oral minoxidil tablets of 2.5 mg is $40 for a supply of 100 tabs. recommend combining oral Finasteride with topical Minoxidil . Minoxidil vs Finasteride: Which is Better? It combines FDA-approved meds — finasteride and minoxidil — that are clinically proven to be most effective when used together, into a single solution that can be easily applied to your scalp. The topical minox uses the enzymes in your scalp and the oral uses the liver. Topical vs Oral Minoxidil? Journal of the European Academy of Dermatology and Venereology, 32(12 . Each group continued treatment for 12 months. Articles:Oral vs topical minoxidil study:https://linkinghub.elsevier.com/retrieve/pii/S0190962219326660Heart rate and mortality:https://www.ncbi.nlm.nih.gov/. It was observed that there were no significant differences between the efficacy of aqueous-based topical 2% nanosuspension of minoxidil and the commercial product in the treatment of AGA ( P > 0.05). In a retrospective assessment and prospective crossover cohort study of 50 male between 20 to 40 years old by Chandrashekar et al. Can women use topical finasteride? DHT in the scalp causes miniaturization of hair follicles in patients suffering from androgenetic alopecia. . No incidence of decreased sexual desire, performance, or sperm count were reported among the patients using topical finasteride. A new study by Raouf and colleagues from Egypt set out to compare the benefits of 5 % topical minoxidil gel, 1 % topical spironolactone gel and a combined 5% minoxidil/1 % spironolactone gel. Topical dutasteride vs. finasteride side effects. Anybody here reccomend oral minoxidil over topical? Minoxidil and finasteride are different medications designed for different purposes. Minoxidil has to be converted by enzyme activity to be utilized by the body. Taking a tablet is the easiest method of a treatment. While being tested, one of the side effects was increased hair growth. Finally, 84.4% of patients who were on oral finasteride for about 2 years and then switched over to topical finasteride with minoxidil maintained good hair density. . Discover the magic of the internet at Imgur, a community powered entertainment destination. What forms do finasteride and minoxidil come in? Oral minoxidil for hair loss At Salford Royal, patients are considered eligible for oral minoxidil treatment if their hair loss has not responded to topical minoxidil or if these products are not tolerated. Out of the 45 male patients who underwent the study, 84.44% maintained good results with a topical Minoxidil-Finasteride combination. Side Effects of Oral Minoxidil. I started minoxidil at around the same time I even began checking my blood work (about 2 years ago), so to discern whats causing it may mean I'll go off it for a few months to see. It was during clinical tests, however, that researchers realized the hair regrowth potential of the medication. There isn't much research comparing topical finasteride and dutasteride. Topical Minoxidil vs Oral Minoxidil Study In a recent study published in the Journal of the American Academy of Dermatology, a 24-week randomized study was done on fifty-two women suffering from female pattern hair loss. Of these, 80% maintained good hair density while on the 5% minoxidil and 0.1% finasteride solution. Nevertheless, when a tablet is consumed it is systemically absorbed. More recently, low doses of oral minoxidil have been used "off-label" to help patients with androgenetic alopecia who prefer daily oral administration . Background: Male Androgenetic Alopecia is a common hair loss disorder that increases with age.The cornerstones of medical management are minoxidil and finasteride.No treatment is completely satisfactory. The first group received once-daily oral finasteride (1 mg/d), while the second group received topical 2% minoxidil (1 mL twice daily). oral will increase your chance of sides and is less effective than the topical. In this study 26 women received oral minoxidil and 26 women received topical minoxidil. Side effects of oral minoxidil therapy are dose related and include low blood pressure, increased heart rate and fluid retention (see page 3). In this open, randomized and comparative study we evaluated the efficacy of oral finasteride and 5% topical minoxidil treatment for 12 months in 65 male patients with mild to severe AGA. There are some challenges associated with switching from topical to oral minoxidil. I've seen posts about hair loss dating as far back as 2004 and . Researchers split the study into two groups, comparing the effectiveness of the finasteride-minoxidil (3%) topical treatment vs. a . Frankly, taking an oral form of minoxidil poses various issues (that are not generally associated with the topical version) and does not boast any tested values with regard to scalp hair. While this makes the process of application slightly trickier than oral medication, it does mean that the effects are felt more locally. But if you have tried minoxidil and didn't receive good results, you should definitely try the topical finasteride. At the 12 month mark, the participants were asked if they would like to continue treatment for another year. Topical minoxidil is used on the scalp by spraying the liquid solution or foam onto the scalp and massaging it in. Scalp pruritus affected 19% of participants in the topical minoxidil group. Patient 1: Dutasteride injections plus oral Dutasteride plus 5% topical Minoxidil at 12-months. Minoxidil as a Hair Loss Treatment. In addition, a 2009 study published in the . However, this is not the case with oral minoxidil. The baseline in the topical minoxidil group was 163.2 hairs per cm2, and at the end of the 24-week trial, it went up to 176.3 hairs per cm2. Oral minoxidil isn't really prescribed as a treatment for androgenetic alopecia because it was originally intended to treat hypertension, but after observing that one of the reported side effects was hair growth, it was later used as a topical to treat hair loss under the trade name Rogaine. At the end of the 24 weeks, oral minoxidil total hair had gone up to 184.7 per cm2. A 120-week study of male subjects with androgenetic alopecia showed that minoxidil was statistically significantly superior to the placebo in increasing hair count. Hair loss is a common problem that can affect both men and women. 7 (2017), all 50 patients used minoxidil 5% and oral 1mg finasteride for 2 years.They then stopped and their treatment differed. Overview of Oral minoxidil vs minoxidil topical for hair growth. They branded this new version 1988 as Rogaine. Rogaine is a topical treatment that includes minoxidil, a medication that is clinically proven to slow the progression of hair loss and regrow some hair. a maximum dose of one diuretic and two other antihypertensive medications) and have had no success. Oral minoxidil was found to be an effective and well-tolerated treatment alternative for healthy patients having difficulty with topical formulations. However, the aqueous-based topical 2% nanosuspension formulation showed better safety and tolerability compared to the marketed profile . Despite the drug's benefits in treating hypertension and hair loss, minoxidil is not appropriate for everyone and may cause significant side effects. DHT Reduction in Scalp and Serum (blood) / Oral vs. Topical finasteride. Automatically receive MPMD articles when they are published: http://bit.ly/2mtASGW———————————— https://www.gorillamind.com/?atid=7 . Dislikes Received: 0. For those getting side effects from oral Minoxidil or fearful of taking it, topical Minoxidil is always a good alternative. In a 6-month, 2018 Thai study with 40 patients, the effectiveness of a topical finasteride-minoxidil blend was reviewed. also works for larger percentage of people taking it. There is some chance that I naturally have a lower WBC count and the topical minoxidil I apply twice daily for the most part may be pushing it slightly out of range. Oral minoxidil vs topical minoxidil pros and cons. In general, topical formulations carry less risk of systemic (whole-body) side effects than oral capsules or tablets, but more studies need to be done to confirm this. Oral minoxidil for hair loss At Salford Royal, patients are considered eligible for oral minoxidil treatment if their hair loss has not responded to topical minoxidil or if these products are not tolerated. Topical versions of minoxidil (brand name: Rogaine) have been used for decades to help slow genetic thinning, but daily compliance with the application is often a barrier to continued use. The first group received once-daily oral finasteride (1 mg/d), while the second group received topical 2% minoxidil (1 mL twice daily). Below are some great hair regrowth results of men who took topical Minoxidil 5% and Dutasteride. While the increase in total hair density was higher in the OM group (12% vs 7.2%), the difference was not statistically significant (P=.10). double‐blind controlled study of the efficacy and safety of topical solution of 0.25% finasteride admixed with 3% minoxidil vs. 3% minoxidil solution in the treatment of male androgenetic alopecia. Adverse events are shown in Table II. Worth mentioning is a study that revealed topical Finasteride as being effective for hair density maintenance after going for an initial treatment with oral finasteride. Minoxidil comes in 2% and 5% formulas. The active ingredient minoxidil was first developed as an oral treatment for hypertension ( 1 ). According to Mayo Clinic, minoxidil topical is an over-the-counter medication. Pretibial edema occurred in 4% of participants in the oral minoxidil group. When this side effect was seen, Minoxidil refined the product after much testing. Some patients followed with this medication immediately, some took an 8-12 month break before starting the pure topical preparation. Dutasteride 0.5 mg was found to be superior to finasteride 1 mg at weeks 12 and 24 at . Poor response to topical minoxidil may occur in individuals with low levels of sulfotransferase enzyme in the hair follicle, which is required to convert the pro-drug . Happy Head offers a very legitimate topical hair loss treatment for men. Hypertrichosis was more common with oral minoxidil (27% oral vs 4% topical), although this [] However, in cases of non-responders and in patients developing irritant or allergic contact dermatitis to the topical formulation, oral minoxidil (OM) can be an option of choice. Oral Minoxidil tablets were used by Ashley and Martin briefly in the early 1990s when standard topical Minoxidil treatments were not strong enough to achieve a decent result. A novel combination topical treatment by the name NuH Hair [topical FNS, dutasteride and minoxidil (MNX)], was formulated by Rafi and Katz (2011). A 2014 study conducted over 29 weeks in 917 men with AGA found oral dutasteride to be more effective than finasteride for the treatment of hair loss. shedding may occur if there was previous regrowth. The use of minoxidil topical for hair growth has been proven to be good. Oral minoxidil was originally used to treat refractory hypertension, while the topical formulation, commonly known as Rogaine, was developed in 1987 for male and female pattern hair loss. Some studies show that higher concentrations of minoxidil are the most effective for hair growth. A study conducted in 2015 examined the effects of using a solution that contained 5% topical minoxidil fortified with 0.1% finasteride after patients were treated initially with the 5% topical minoxidil solution and oral finasteride over the course of two years. Edited January 5 by ciaus 2 Melvin- Moderator It works as a direct vasodilator, and it's still used in patients with resistant hypertension. The majority of the time, hair loss is treated with a combination of either oral or topical Finasteride along with topical Minoxidil - another treatment known to prevent further hair loss and even increase hair growth. Topical minoxidil 2-5%, oral finasteride, and low-level laser therapy are current the standard first-line treatments for androgenetic alopecia (AGA). Minoxidil (topical aerosol) 1 ML topical foam (usually 5% concentration) ~60%. Topical minoxidil -- don't think it helped after trying it for a couple years, I've stopped using it recently Oral Spironolactone -- don't think it helped but I still take it Switched to Yasmin BC (supposedly a hair friendly pill) -- don't think it helped but I still take it Minoxidil, better known by the brand name Rogaine, is a topical hair loss drug. topical minoxidil, a nonsignificant difference (P ¼.09). 450 Chinese MAGA patients were randomly assigned to receive finasteride (n = 160), minoxidil (n = 130) and combined medication (n = 160) for 12 months.The patients returned to the clinic every 3 months for efficacy . Read more; Disclaimer: The purpose of this website is to provide the public with general information on hair restoration and related medical topics.Information provided on this site should not be used for medical diagnosis and/or treatment. As of the moment, there seem to be more studies looking at applying topical finasteride and dutasteride together than testing either individually. In men the recommended percentage is 5% minoxidil. minoxidil was first introduced as an oral medication for the treatment of severe and recalcitrant hypertension in the 1970s.1coincidentally, physicians observed hair regrowth and generalized hypertrichosis in balding patients, which led to the development of a topical minoxidil formulation for treating androgenetic alopecia (aga) first in male … Originally intended as an oral medication for severe hypertension, minoxidil became a likely treatment option for hair loss when cases of hypertrichosis were reported in patients after use.. Topical minoxidil works as a hair growth stimulator.This medication shortens the telogen phase, causing the dormant hair follicles to enter into a premature anagen phase. cons I've heard: not good for your heart. Finasteride is more commonly known for its tablet form to treat benign prostatic hyperplasia (BPH), brand name Proscar and male pattern hair loss (alopecia), brand name Propecia. It was reported that 1 mg oral finasteride and 5% topical minoxidil are safe and effective. Oral minoxidil is most effective in hypertension patients who have tried other medications (e.g. A combination of minoxidil and Without doubt, oral finasteride offers a far greater convenience. research confirms that it is more effective. Logically, the topical will only work in the area it is applied, while the oral covers the entire scalp. Therefore, the potential for side effects should inform your decision on what to use. Oral vs Topical Finasteride Research. Furthermore, it may help to discuss these issues . In this randomized comparative study, 52 women with female pattern hair loss (Sinclair's stage 2-4) received oral minoxidil (OM) 1 mg or topical minoxidil (TM) 5% (1 mL) once daily for 24 weeks. topical gets it directly onto the scalp to improve blood flow. However, studies describing their effects in Chinese individuals are scarce. the scalp, as a spray or lotion. Oral minoxidil may have a role in situations where there is irritation or contact allergy, or if diligent use for 6 to 9 months shows no benefit (and is objectively measured). Originally used to treat high blood pressure, Rogaine is . Not everybody is blessed with good enzymes in their scalp but the liver is pretty much a processing sure thing so more people are likely to respond. Roman - only $12 per month. The treatment was randomized, and the women were given 1 mg of oral minoxidil or 5 % of topical minoxidil. Abstract. Just because you may now only have frontal or crown balding, don't be fooled as the early miniaturization may be all over your scalp including some of the area you do not recognize the miniaturization as it will be less than 50% of the hairy areas. Minoxidil is a topical formulation that was first developed as an oral tablet for the treatment of hypertension . 15 male patients were asked to apply the solution daily for nine months and were given the option of adding three further components to their treatment protocol: 1) oral FNS 1 mg daily 2) topical MNX . RCT of 50 male patients treated with topical minoxidil + oral finasteride for 2 years THEN followed by topical medication only consisting of topical minoxidil + topical finasteride. Lift your spirits with funny jokes, trending memes, entertaining gifs, inspiring stories, viral videos, and so much more. Spironolactone is a diuretic that may be used to remove excess fluid (edema) from the body, lower blood pressure, or treat hyperaldosteronism. minoxidil topical may also be used for purposes not listed in this medication guide. Typically, topical minoxidil is safer than oral minoxidil when you are considering higher dosages. if you are a non responder to topical thats just the luck of the draw. In addition, oral minoxidil has also been investigated by the medical community as a potential agent for male pattern hair loss. Prescribed for Alopecia. Researchers concluded by stating the 5% . Aims and Objectives: This study compared Topical Minoxidil 5%+Finasteride 0.1% combination (Group A) and Topical Minoxidil 5%+Oral Finasteride 1 mg/day (Group B) in treating Male . The study showed that the baseline for total hair per square centimeter (cm2) in the oral minoxidil group was 164.6. Some people find using oral medications easier than lotion. 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